This changed the focus of a few drug discovery projects. Using bioinformatics, he showed that the CLCA protein family, believed at the time to be ion channels and drug targets for asthma and COPD, were in fact metalloproteases. After the postdoc, he spent six years at AstraZeneca R&D Lund, Sweden, working on bioinformatics aspects of early target discovery in respiratory diseases. Later these proteins turned out to be crucial to inflammasome and the innate immune system activation. Among others, he identified the novel NLRP protein family and the novel pyrin/PAAD structural domains within. There, he worked on bioinformatics identification and characterization of novel apoptosis-related proteins. Adam Godzik at The Scripps Research Institute, and later at The Burnham Institute. He moved to San Diego as a postdoctoral fellow to the lab of Dr. Andrzej Bierzyński, and focusing on structural bioinformatics of calcium binding proteins. in biophysics in 1997 from Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, working with Prof. in biophysics from University of Warsaw, Poland. Kinsley dissertation award from Indiana University School of Medicine, a K99/R00 Pathway to Independence award from the National Institutes of Health, and Cancer Prevention Research Institute of Texas (CPRIT) Recruitment of First-Time, Tenure-Track Faculty Member award. In 2015, he joined the faculty at UT Southwestern as an Assistant Professor in the Department of Molecular Biology, where he is an Endowed Scholar in Medical Science. As part of this work, he identified Fam20C as the bona fide Golgi casein kinase, an enzyme that escaped identification for many years.

There, he discovered a novel family of secreted kinases that phosphorylate proteins destined for secretion from the cell. Jack Dixon as a postdoctoral fellow at the University of California, San Diego. In 2010, Vinnie joined the laboratory of Dr.

As a graduate student, Vinnie made several important contributions to understanding how elevated levels of glycogen phosphate cause Lafora disease, a deadly form of epilepsy. in biochemistry and molecular biology from Indiana University, where he worked with Dr. in chemistry and biology from the University of Indianapolis.

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